Hungary



UNITED STATES PATENT OFFICE.

HUGO VON PERGER, OF REICHENBERG, BOHEMIA, AUSTRIA-HUNGARY,

' ASSIGNOR TO THE SOCIETY OF CHEMICAL INDUSTRY, OE SAME PLACE.

PRODUCTION OF PHENYL-METHYL OXYQUlNlClNE.

1'. LCIPICATION forming part of Letters Patent No. 348,483, dated August 31, 1886 Application filed June 10, 1886. Serial No. 201,743. (Specimens To all whom it may concern.-

Be it known that I, IIUGO voN PERGER, a citizen of Austria, residing at Reichenberg, Bohemia, in the Empire of Austriallungary, have invented new and useful Improvements in the Manufacture of Derivatives ofQninicine by the action of Hydrazobenzole upon Acetylacetic Ether, of which the following isaspecifieation.

This invention relates to the production of derivatives of qninicine by the action of hydrazobenzole upon acetylacetie ether.

In carrying out my invention I proceed as follows: Ten parts, by weight, of hydrazobenzole are heated with ten to fifteen parts, by weight, of acetylacetic ether during the space ofl'our or five hours at from 90 to 130 centigrade. After cooling, the ineltis repeatedly boiled out with diluted mnriatic acid. The liquids are neutralized by the addition of ammoniac. The thus separated crystalline mass is collected on a filter, and dissolved in stronglydiluted boiling sulphuric acid and filtered. Upon cooling the raw phenyl -1nethyl oxyquinicine crystallizes, and can be obtained in 2 I 0 I o \Vhat l. clann as new and origlnahand deslre to secure by Letters Patent, is

The production 0t phenyl-methyl oxyquinicine by the action of hydrazobenzole upon acetylacetic ether.

In testimony whereof I have hereunto set my hand and seal in the presence of two subscribing witnesses.

nUoo VON PERGER. [n 3.]

Vitnesses:

EDWARD Penman, XVILIL FEIs'rING.

Letters Patent No. 348,483.

It is hereby certified that the residence of the assignee in Letters Patent No. 348,483, granted August 31, 1886, upon the application of Hugo Von Perger, of Reichenberg, Bohemia, Austria-Hungary, for an improvement in Production of Phenyi-Methyl Oxyquinicine, was erroneously written and printed of same place, Whereas said residence Switzerland and that the said Letters therein that the same may conform to the should have been written and printed Basie,

Patent should be read with this correction record of the casein the Patent Ofifice.

Signed, countersigned, and sealed this 12th day of October, A. D. 1886.

D. L. HAWKINS, Acting Secretary of the Interim" [SEAL] Gountersigned:

R. B. VANCE, v

Acting Commissioner of Patents. 

